S5N (p.Ser5Asn) variant of CUL3 (Cullin-3)
S5N (p.Ser5Asn) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.22 / 1. The record also includes population frequency data and structural context.
S5N (p.Ser5Asn) variant details
- p.Ser5Asn
- TOPMed rs1009417526
- gnomAD rs1009417526
- Missense
- Variant Prioritization Score for Impact Estimate 0.217
- REVEL 0.05
- CADD 19.30
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available