S2* (p.Ser2Ter) variant of CUL3 (Cullin-3)

S2* (p.Ser2Ter) in CUL3 (Cullin-3) is a protein-truncating change. Clinical records from UniProt describe it as variant assessed as somatic; high impact. The available variant effect predictions contribute to a CATVariant prioritization score of 0.58 / 1. The record also includes population frequency data and structural context.

S2* (p.Ser2Ter) variant details