S10R (p.Ser10Arg) variant of CUL3 (Cullin-3)
S10R (p.Ser10Arg) in CUL3 (Cullin-3) is a missense change. Clinical records from ClinVar and UniProt describe it as likely benign in the context of not provided. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
S10R (p.Ser10Arg) variant details
- p.Ser10Arg
- Ensembl rs2106331331
- Likely benign
- not provided
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.12
- CADD 22.60
- PolyPhen-2 0.04
- SIFT 0.31
- ClinVar: Likely benign (not provided)
- UniProt: Likely benign
- Population evidence available
- Structural context available