S10G (p.Ser10Gly) variant of CUL3 (Cullin-3)
S10G (p.Ser10Gly) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.25 / 1. The record also includes population frequency data and structural context.
S10G (p.Ser10Gly) variant details
- p.Ser10Gly
- TOPMed rs1695545689
- Missense
- Variant Prioritization Score for Impact Estimate 0.247
- REVEL 0.06
- CADD 21.20
- PolyPhen-2 0.00
- SIFT 0.45
- Most common in the East Asian population (allele frequency 0.00015)
- Structural context available