R46S (p.Arg46Ser) variant of CUL3 (Cullin-3)
R46S (p.Arg46Ser) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data and structural context.
R46S (p.Arg46Ser) variant details
- p.Arg46Ser
- ExAC rs745998120
- gnomAD rs745998120
- Missense
- Variant Prioritization Score for Impact Estimate 0.406
- REVEL 0.23
- CADD 23.30
- PolyPhen-2 0.39
- SIFT 0.08
- Population evidence available
- Structural context available