R19W (p.Arg19Trp) variant of CUL3 (Cullin-3)
R19W (p.Arg19Trp) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data and structural context.
R19W (p.Arg19Trp) variant details
- p.Arg19Trp
- Ensembl rs2106331293
- Missense
- Variant Prioritization Score for Impact Estimate 0.47
- REVEL 0.46
- CADD 29.10
- PolyPhen-2 0.98
- SIFT 0.00
- Most common in the HGDP:YAKUT population (allele frequency 0.04)
- Structural context available