M23L (p.Met23Leu) variant of CUL3 (Cullin-3)
M23L (p.Met23Leu) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.43 / 1. The record also includes population frequency data and structural context.
M23L (p.Met23Leu) variant details
- p.Met23Leu
- Ensembl rs2106305263
- Missense
- Variant Prioritization Score for Impact Estimate 0.427
- REVEL 0.30
- CADD 23.00
- PolyPhen-2 0.05
- SIFT 0.36
- Population evidence available
- Structural context available