I18T (p.Ile18Thr) variant of CUL3 (Cullin-3)
I18T (p.Ile18Thr) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data and structural context.
I18T (p.Ile18Thr) variant details
- p.Ile18Thr
- Ensembl rs2106331297
- Missense
- Variant Prioritization Score for Impact Estimate 0.345
- REVEL 0.29
- CADD 26.00
- PolyPhen-2 0.77
- SIFT 0.01
- Population evidence available
- Structural context available