G7V (p.Gly7Val) variant of CUL3 (Cullin-3)
G7V (p.Gly7Val) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.27 / 1. The record also includes population frequency data and structural context.
G7V (p.Gly7Val) variant details
- p.Gly7Val
- TOPMed rs1695545965
- Missense
- Variant Prioritization Score for Impact Estimate 0.27
- REVEL 0.09
- CADD 21.70
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the Non-Finnish European population (allele frequency 2.9e-05)
- Structural context available