G51S (p.Gly51Ser) variant of CUL3 (Cullin-3)
G51S (p.Gly51Ser) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.59 / 1. The record also includes population frequency data and structural context.
G51S (p.Gly51Ser) variant details
- p.Gly51Ser
- Ensembl rs2106304724
- Missense
- Variant Prioritization Score for Impact Estimate 0.594
- REVEL 0.47
- CADD 24.40
- PolyPhen-2 0.59
- SIFT 0.10
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available