E27K (p.Glu27Lys) variant of CUL3 (Cullin-3)
E27K (p.Glu27Lys) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.65 / 1. The record also includes population frequency data and structural context.
E27K (p.Glu27Lys) variant details
- p.Glu27Lys
- cosmic curated COSV52366
- Ensembl rs2106305165
- Missense
- Variant Prioritization Score for Impact Estimate 0.65
- REVEL 0.56
- CADD 25.00
- PolyPhen-2 0.72
- SIFT 0.10
- Population evidence available
- Structural context available