D35G (p.Asp35Gly) variant of CUL3 (Cullin-3)
D35G (p.Asp35Gly) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.42 / 1. The record also includes population frequency data and structural context.
D35G (p.Asp35Gly) variant details
- p.Asp35Gly
- ExAC rs749470638
- gnomAD rs749470638
- Missense
- Variant Prioritization Score for Impact Estimate 0.419
- REVEL 0.29
- CADD 23.00
- PolyPhen-2 0.01
- SIFT 0.27
- Most common in the East Asian population (allele frequency 2.5e-05)
- Structural context available