D35E (p.Asp35Glu) variant of CUL3 (Cullin-3)
D35E (p.Asp35Glu) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
D35E (p.Asp35Glu) variant details
- p.Asp35Glu
- gnomAD rs1165128140
- Missense
- Variant Prioritization Score for Impact Estimate 0.342
- REVEL 0.32
- CADD 14.20
- PolyPhen-2 0.02
- SIFT 0.79
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available