D13N (p.Asp13Asn) variant of CUL3 (Cullin-3)
D13N (p.Asp13Asn) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
D13N (p.Asp13Asn) variant details
- p.Asp13Asn
- cosmic curated COSV52364
- Ensembl rs2969802
- Missense
- Variant Prioritization Score for Impact Estimate 0.288
- REVEL 0.10
- AlphaMissense 0.94
- MetaLR 0.26
- MetaSVM -0.75
- CADD 21.40
- PolyPhen-2 0.85
- Most common in the 1KG:CLM population (allele frequency 0.0053)
- Structural context available