A20T (p.Ala20Thr) variant of CUL3 (Cullin-3)
A20T (p.Ala20Thr) in CUL3 (Cullin-3) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A20T (p.Ala20Thr) variant details
- p.Ala20Thr
- Ensembl rs2106331279
- Missense
- Variant Prioritization Score for Impact Estimate 0.329
- REVEL 0.17
- CADD 23.90
- PolyPhen-2 0.80
- SIFT 0.09
- Most common in the Middle Eastern population (allele frequency 0.0007)
- Structural context available