T34A (p.Thr34Ala) variant of CTNNA1 (Catenin alpha-1)
T34A (p.Thr34Ala) in CTNNA1 (Catenin alpha-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
T34A (p.Thr34Ala) variant details
- p.Thr34Ala
- gnomAD 5-138782024-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.344
- REVEL 0.17
- CADD 20.80
- PolyPhen-2 0.01
- SIFT 0.80
- Most common in the South Asian population (allele frequency 1.2e-05)
- Structural context available
- Literature evidence available