R27T (p.Arg27Thr) variant of CTNNA1 (Catenin alpha-1)
R27T (p.Arg27Thr) in CTNNA1 (Catenin alpha-1) is a protein-truncating change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.31 / 1. The record also includes population frequency data, published literature, and structural context.
R27T (p.Arg27Thr) variant details
- p.Arg27Thr
- rs1161711503
- gnomAD 5-138781999-TGA-T
- Frameshift
- Variant Prioritization Score for Impact Estimate 0.307
- CADD 32.00
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available