K12K (p.Lys12Lys) variant of CTNNA1 (Catenin alpha-1)
K12K (p.Lys12Lys) in CTNNA1 (Catenin alpha-1) is a synonymous change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.28 / 1. The record also includes population frequency data, published literature, and structural context.
K12K (p.Lys12Lys) variant details
- p.Lys12Lys
- rs1755159437
- gnomAD 5-138781960-G-A
- Synonymous
- Variant Prioritization Score for Impact Estimate 0.278
- AlphaMissense 0.87
- MetaLR 0.28
- MetaSVM -0.76
- CADD 8.41
- PolyPhen-2 0.69
- SIFT 0.16
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available
- Literature evidence available