D14G (p.Asp14Gly) variant of CTNNA1 (Catenin alpha-1)
D14G (p.Asp14Gly) in CTNNA1 (Catenin alpha-1) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.62 / 1. The record also includes population frequency data, published literature, and structural context.
D14G (p.Asp14Gly) variant details
- p.Asp14Gly
- gnomAD 5-138781965-A-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.623
- REVEL 0.60
- CADD 27.80
- PolyPhen-2 0.58
- SIFT 0.01
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available