V73L (p.Val73Leu) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
V73L (p.Val73Leu) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.47 / 1. The record also includes population frequency data, published literature, and structural context.
V73L (p.Val73Leu) variant details
- p.Val73Leu
- gnomAD 2-203870693-G-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.474
- MetaLR 0.08
- MetaSVM -1.01
- CADD 15.20
- PolyPhen-2 0.00
- SIFT 1.00
- Population evidence available
- Structural context available
- Literature evidence available