V57M (p.Val57Met) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
V57M (p.Val57Met) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.53 / 1. The record also includes population frequency data, published literature, and structural context.
V57M (p.Val57Met) variant details
- p.Val57Met
- gnomAD 2-203870645-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.532
- MetaLR 0.32
- MetaSVM -0.73
- CADD 22.70
- PolyPhen-2 0.49
- SIFT 0.10
- Population evidence available
- Structural context available
- Literature evidence available