V33F (p.Val33Phe) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
V33F (p.Val33Phe) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.19 / 1. The record also includes population frequency data, published literature, and structural context.
V33F (p.Val33Phe) variant details
- p.Val33Phe
- gnomAD 2-203868039-G-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.188
- MetaLR 0.10
- MetaSVM -0.97
- CADD 12.50
- PolyPhen-2 0.08
- SIFT 0.47
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available