S79N (p.Ser79Asn) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
S79N (p.Ser79Asn) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
S79N (p.Ser79Asn) variant details
- p.Ser79Asn
- ExAC rs754725143
- TOPMed rs754725143
- gnomAD rs754725143
- Missense
- Variant Prioritization Score for Impact Estimate 0.124
- MetaLR 0.06
- MetaSVM -1.05
- CADD 0.38
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available