S62F (p.Ser62Phe) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
S62F (p.Ser62Phe) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.46 / 1. The record also includes population frequency data, published literature, and structural context.
S62F (p.Ser62Phe) variant details
- p.Ser62Phe
- gnomAD 2-203870661-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.463
- MetaLR 0.13
- MetaSVM -0.98
- CADD 12.50
- PolyPhen-2 0.05
- SIFT 0.78
- Population evidence available
- Structural context available
- Literature evidence available