Q76K (p.Gln76Lys) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
Q76K (p.Gln76Lys) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data, published literature, and structural context.
Q76K (p.Gln76Lys) variant details
- p.Gln76Lys
- gnomAD 2-203870702-C-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.301
- MetaLR 0.13
- MetaSVM -0.93
- CADD 13.30
- PolyPhen-2 0.02
- SIFT 0.20
- Most common in the REMAINING population (allele frequency 1.7e-05)
- Structural context available
- Literature evidence available