P32L (p.Pro32Leu) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
P32L (p.Pro32Leu) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.60 / 1. The record also includes population frequency data and structural context.
P32L (p.Pro32Leu) variant details
- p.Pro32Leu
- TOPMed rs1413571467
- gnomAD rs1413571467
- Missense
- Variant Prioritization Score for Impact Estimate 0.599
- MetaLR 0.23
- MetaSVM -0.83
- CADD 22.90
- PolyPhen-2 0.00
- SIFT 0.01
- Most common in the REMAINING population (allele frequency 0.00048)
- Structural context available