N14T (p.Asn14Thr) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
N14T (p.Asn14Thr) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.14 / 1. The record also includes population frequency data, published literature, and structural context.
N14T (p.Asn14Thr) variant details
- p.Asn14Thr
- gnomAD 2-203867983-A-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.141
- MetaLR 0.05
- MetaSVM -1.04
- CADD 5.93
- PolyPhen-2 0.01
- SIFT 0.25
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available