L29F (p.Leu29Phe) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
L29F (p.Leu29Phe) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.35 / 1. The record also includes population frequency data, published literature, and structural context.
L29F (p.Leu29Phe) variant details
- p.Leu29Phe
- gnomAD 2-203868027-C-T
- Missense
- Variant Prioritization Score for Impact Estimate 0.353
- MetaLR 0.15
- MetaSVM -0.98
- CADD 22.40
- PolyPhen-2 0.85
- SIFT 0.16
- Population evidence available
- Structural context available
- Literature evidence available