L28V (p.Leu28Val) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
L28V (p.Leu28Val) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data, published literature, and structural context.
L28V (p.Leu28Val) variant details
- p.Leu28Val
- gnomAD 2-203868024-C-G
- Missense
- Variant Prioritization Score for Impact Estimate 0.338
- MetaLR 0.08
- MetaSVM -0.89
- CADD 15.80
- PolyPhen-2 0.47
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available