L24H (p.Leu24His) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
L24H (p.Leu24His) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.41 / 1. The record also includes population frequency data, published literature, and structural context.
L24H (p.Leu24His) variant details
- p.Leu24His
- gnomAD 2-203868013-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.411
- MetaLR 0.07
- MetaSVM -1.02
- CADD 11.70
- PolyPhen-2 0.15
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available