K65E (p.Lys65Glu) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
K65E (p.Lys65Glu) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
K65E (p.Lys65Glu) variant details
- p.Lys65Glu
- gnomAD rs1346241200
- Missense
- Variant Prioritization Score for Impact Estimate 0.316
- MetaLR 0.23
- MetaSVM -0.85
- CADD 20.60
- PolyPhen-2 0.10
- SIFT 0.11
- Most common in the Finnish in Finland (FIN) population (allele frequency 1.9e-05)
- Structural context available