K10E (p.Lys10Glu) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
K10E (p.Lys10Glu) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
K10E (p.Lys10Glu) variant details
- p.Lys10Glu
- ESP rs146541851
- ExAC rs146541851
- TOPMed rs146541851
- gnomAD rs146541851
- Missense
- Variant Prioritization Score for Impact Estimate 0.126
- MetaLR 0.05
- MetaSVM -1.02
- CADD 0.97
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the African/African-American population (allele frequency 7.2e-05)
- Structural context available