I31V (p.Ile31Val) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
I31V (p.Ile31Val) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
I31V (p.Ile31Val) variant details
- p.Ile31Val
- ExAC rs774434261
- gnomAD rs774434261
- Missense
- Variant Prioritization Score for Impact Estimate 0.382
- MetaLR 0.06
- MetaSVM -1.09
- CADD 15.80
- PolyPhen-2 0.01
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 3.7e-05)
- Structural context available