F26L (p.Phe26Leu) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
F26L (p.Phe26Leu) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.23 / 1. The record also includes population frequency data, published literature, and structural context.
F26L (p.Phe26Leu) variant details
- p.Phe26Leu
- gnomAD 2-203868018-T-C
- Missense
- Variant Prioritization Score for Impact Estimate 0.234
- MetaLR 0.03
- MetaSVM -0.95
- CADD 0.79
- PolyPhen-2 0.00
- SIFT 0.82
- Most common in the Non-Finnish European population (allele frequency 9e-07)
- Structural context available
- Literature evidence available