F26I (p.Phe26Ile) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
F26I (p.Phe26Ile) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.24 / 1. The record also includes population frequency data, published literature, and structural context.
F26I (p.Phe26Ile) variant details
- p.Phe26Ile
- gnomAD 2-203868018-T-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.238
- MetaLR 0.05
- MetaSVM -1.04
- CADD 2.90
- PolyPhen-2 0.02
- SIFT 0.12
- Most common in the Non-Finnish European population (allele frequency 1.8e-06)
- Structural context available
- Literature evidence available