E59K (p.Glu59Lys) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
E59K (p.Glu59Lys) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.52 / 1. The record also includes population frequency data, published literature, and structural context.
E59K (p.Glu59Lys) variant details
- p.Glu59Lys
- gnomAD 2-203870651-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.519
- MetaLR 0.15
- MetaSVM -1.00
- CADD 22.50
- PolyPhen-2 0.03
- SIFT 0.29
- Population evidence available
- Structural context available
- Literature evidence available