A61T (p.Ala61Thr) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
A61T (p.Ala61Thr) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.34 / 1. The record also includes population frequency data and structural context.
A61T (p.Ala61Thr) variant details
- p.Ala61Thr
- gnomAD rs1221748361
- Missense
- Variant Prioritization Score for Impact Estimate 0.339
- MetaLR 0.06
- MetaSVM -1.00
- CADD 13.90
- PolyPhen-2 0.00
- SIFT 0.38
- Most common in the REMAINING population (allele frequency 3.3e-05)
- Structural context available