A37T (p.Ala37Thr) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
A37T (p.Ala37Thr) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.64 / 1. The record also includes population frequency data, published literature, and structural context.
A37T (p.Ala37Thr) variant details
- p.Ala37Thr
- gnomAD 2-203868051-G-A
- Missense
- Variant Prioritization Score for Impact Estimate 0.638
- MetaLR 0.24
- MetaSVM -0.78
- CADD 29.80
- PolyPhen-2 0.17
- SIFT 0.01
- Population evidence available
- Structural context available
- Literature evidence available