A11G (p.Ala11Gly) variant of CTLA4 (Cytotoxic T-lymphocyte protein 4)
A11G (p.Ala11Gly) in CTLA4 (Cytotoxic T-lymphocyte protein 4) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.33 / 1. The record also includes population frequency data and structural context.
A11G (p.Ala11Gly) variant details
- p.Ala11Gly
- gnomAD rs1484954450
- Missense
- Variant Prioritization Score for Impact Estimate 0.334
- MetaLR 0.05
- MetaSVM -1.07
- CADD 4.57
- PolyPhen-2 0.00
- SIFT 0.12
- Most common in the Ashkenazi Jewish population (allele frequency 3.8e-05)
- Structural context available