V33F (p.Val33Phe) variant of CRBN (Protein cereblon)
V33F (p.Val33Phe) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
V33F (p.Val33Phe) variant details
- p.Val33Phe
- TOPMed rs1335338146
- gnomAD rs1335338146
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.13
- CADD 19.60
- PolyPhen-2 0.06
- SIFT 0.09
- Most common in the African/African-American population (allele frequency 2.8e-05)
- Structural context available