T51P (p.Thr51Pro) variant of CRBN (Protein cereblon)
T51P (p.Thr51Pro) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.32 / 1. The record also includes population frequency data and structural context.
T51P (p.Thr51Pro) variant details
- p.Thr51Pro
- ExAC rs764115779
- gnomAD rs764115779
- Missense
- Variant Prioritization Score for Impact Estimate 0.32
- REVEL 0.23
- CADD 22.70
- PolyPhen-2 0.00
- SIFT 0.28
- Most common in the HGDP:YAKUT population (allele frequency 0.8)
- Structural context available