S38T (p.Ser38Thr) variant of CRBN (Protein cereblon)
S38T (p.Ser38Thr) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.16 / 1. The record also includes population frequency data and structural context.
S38T (p.Ser38Thr) variant details
- p.Ser38Thr
- gnomAD rs1157434006
- Missense
- Variant Prioritization Score for Impact Estimate 0.16
- REVEL 0.03
- CADD 14.80
- PolyPhen-2 0.01
- SIFT 0.21
- Most common in the Non-Finnish European population (allele frequency 0.00028)
- Structural context available