Q8P (p.Gln8Pro) variant of CRBN (Protein cereblon)
Q8P (p.Gln8Pro) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.11 / 1. The record also includes population frequency data and structural context.
Q8P (p.Gln8Pro) variant details
- p.Gln8Pro
- ESP rs147395766
- ExAC rs147395766
- TOPMed rs147395766
- gnomAD rs147395766
- Missense
- Variant Prioritization Score for Impact Estimate 0.111
- REVEL 0.05
- CADD 17.80
- PolyPhen-2 0.00
- SIFT 0.17
- Most common in the HGDP:YAKUT population (allele frequency 0.8)
- Structural context available