Q115E (p.Gln115Glu) variant of CRBN (Protein cereblon)
Q115E (p.Gln115Glu) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.38 / 1. The record also includes population frequency data and structural context.
Q115E (p.Gln115Glu) variant details
- p.Gln115Glu
- TOPMed rs966130308
- Missense
- Variant Prioritization Score for Impact Estimate 0.383
- REVEL 0.13
- CADD 21.90
- PolyPhen-2 0.18
- SIFT 0.34
- Most common in the HGDP:PATHAN population (allele frequency 0.021)
- Structural context available