N16Y (p.Asn16Tyr) variant of CRBN (Protein cereblon)
N16Y (p.Asn16Tyr) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.29 / 1. The record also includes population frequency data and structural context.
N16Y (p.Asn16Tyr) variant details
- p.Asn16Tyr
- TOPMed rs1255060716
- gnomAD rs1255060716
- Missense
- Variant Prioritization Score for Impact Estimate 0.289
- REVEL 0.13
- CADD 31.00
- PolyPhen-2 0.99
- SIFT 0.01
- Most common in the 1KG:MXL population (allele frequency 0.0081)
- Structural context available