N16T (p.Asn16Thr) variant of CRBN (Protein cereblon)
N16T (p.Asn16Thr) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.26 / 1. The record also includes population frequency data and structural context.
N16T (p.Asn16Thr) variant details
- p.Asn16Thr
- ExAC rs755209533
- gnomAD rs755209533
- Missense
- Variant Prioritization Score for Impact Estimate 0.261
- REVEL 0.09
- CADD 30.00
- PolyPhen-2 0.96
- SIFT 0.03
- Most common in the Non-Finnish European population (allele frequency 2.2e-05)
- Structural context available