M89V (p.Met89Val) variant of CRBN (Protein cereblon)
M89V (p.Met89Val) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.12 / 1. The record also includes population frequency data and structural context.
M89V (p.Met89Val) variant details
- p.Met89Val
- ExAC rs768172056
- TOPMed rs768172056
- gnomAD rs768172056
- Missense
- Variant Prioritization Score for Impact Estimate 0.122
- REVEL 0.08
- CADD 13.40
- PolyPhen-2 0.00
- SIFT 1.00
- Most common in the HGDP:KALASH population (allele frequency 0.14)
- Structural context available