M88V (p.Met88Val) variant of CRBN (Protein cereblon)
M88V (p.Met88Val) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.13 / 1. The record also includes population frequency data and structural context.
M88V (p.Met88Val) variant details
- p.Met88Val
- ExAC rs753340354
- TOPMed rs753340354
- gnomAD rs753340354
- Missense
- Variant Prioritization Score for Impact Estimate 0.132
- REVEL 0.08
- CADD 13.30
- PolyPhen-2 0.00
- SIFT 0.33
- Most common in the HGDP:BIAKA population (allele frequency 0.068)
- Structural context available