M64T (p.Met64Thr) variant of CRBN (Protein cereblon)
M64T (p.Met64Thr) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.40 / 1. The record also includes population frequency data and structural context.
M64T (p.Met64Thr) variant details
- p.Met64Thr
- ExAC rs771285272
- TOPMed rs771285272
- gnomAD rs771285272
- Missense
- Variant Prioritization Score for Impact Estimate 0.402
- REVEL 0.25
- CADD 23.30
- PolyPhen-2 0.44
- SIFT 0.00
- Most common in the HGDP:PATHAN population (allele frequency 0.021)
- Structural context available