M31V (p.Met31Val) variant of CRBN (Protein cereblon)
M31V (p.Met31Val) in CRBN (Protein cereblon) is a missense change. The available variant effect predictions contribute to a CATVariant prioritization score of 0.30 / 1. The record also includes population frequency data and structural context.
M31V (p.Met31Val) variant details
- p.Met31Val
- ExAC rs768947812
- gnomAD rs768947812
- Missense
- Variant Prioritization Score for Impact Estimate 0.299
- REVEL 0.13
- CADD 15.40
- PolyPhen-2 0.00
- SIFT 0.30
- Most common in the HGDP:BIAKA population (allele frequency 0.091)
- Structural context available